​Yes, you can use Microsoft Access as a frontend to your MySQL database. MS Access is not limited to pairing with Microsoft SQL Server.
 
Microsoft Access is an exceptional tool for building user-friendly database applications. Access is one of the top selling rapid application development tools on the market. The programming tools Microsoft includes in Access mean less code writing. This reality just simply saves programming time. In addition, average users can learn to do basic things with their own data because they can use wizards instead of writing code.
 
However – there are still a lot of misconceptions about MS Access capabilities. One of the biggest misconceptions is that Access can only be paired with Microsoft products like MS Excel or SQL Server. These misconceptions are just simply false. One of the things that makes Access such a great user-friendly data management tool is its ability to integrate data from a wide variety of sources. Your organization is not limited to using MS Access with only Microsoft products.
 
It is not uncommon for smaller organizations to use open-source data management tools. MySQL is one of the more often used open-source database applications. And – yes – you can use MS Access with MySQL. Following is one example of how a small organization might make use of pairing MS Access with MySQL.

In 2014 I wrote the LinkedIn article: If you're looking at OFFICE 365, and you use Microsoft Access, look harder. At the time, Office 365 fell short of my expectations, mostly because of its treatment of MS Access. Initial publicity about MS Office 365 promised the ability to move MS Access databases to their cloud server. But, as my clients moved to Office 365, we discovered Microsoft promises of cloud capabilities for MS Access were inadequate. Complex Access databases could not be used from the cloud platform without major revision.

​Over the years folks have asked me about using MS Access in a remote environment. In time, using a remote desktop setup surfaced as the best remote environment solution for MS Access.